Project ALS Family
Joseph Klim, PhD
Postdoctoral Fellow, Harvard University
ALS is a fatal neurodegenerative disorder caused by the loss of motor neurons, but why these specific types of neurons are lost in this devastating disease remains a mystery. Based on pathological and genetic findings, failures in the motor neuron’s ability to cleared unwanted proteins is a potential cause of ALS. As a Tom Kirchhoff Family postdoctoral fellow, I will leverage my background in chemical and stem cell biology to determine how failures in protein destruction can lead to motor neuron loss. I find inspiration through my interactions with the broader Project ALS community to constantly think about ALS at the molecular level with the long-term goal of demystifying ALS.