Project ALS Family
Mackenzie Weygandt Amoroso
PhD Candidate, Department of Molecular and Cellular Biology, Harvard University
Project ALS has been at the forefront of supporting basic and translational research for nearly two decades. I was fortunate to do research in their stem cell laboratory from 2007 - 2012, where I was part of a team that built the first models of ALS-in-a-dish by using induced pluripotent stem cells to make motor neurons - the cells that die in ALS. Now, I am completing my PhD at Harvard University where I continue to work on the motor system. I use optogenetics, skilled mouse behaviors, electrophysiology, and two photon microscopy to record the activity of neurons (including motor neurons) in awake and behaving mice.