The current issue of Neuroscience journal is dedicated to the staggering contributions to science made by longtime Project ALS Research Advisory Board Chair Thomas M. Jessell, PhD, before his death from the rare neurodegenerative disease progressive supranuclear palsy on April 28, 2019, at 67.

While COVID-19 profoundly affected its day-to-day operations, The Project ALS Therapeutics Core at Columbia generated new approaches to disease modeling and genetic engineering technologies in 2020.

Five years ago, Raleigh, North Carolina’s own Chris Combs, a loving husband and father of three young children, was diagnosed out of nowhere with ALS.